Post by Amtram on Apr 3, 2014 11:18:15 GMT -5
Not approved yet, but they've gotten funding because of promising preliminary findings.
The company has a description of Neurovance up, and I wanted to share this piece -
Personally, I'm skeptical of the overuse of/addiction to stimulants idea that propels a lot of this research and gets so much media attention. If you actually have ADHD, you're not all that likely to have a problem with stimulants. OTOH, medications like these work more like antidepressants (and sometimes antipsychotics) and take a while to start working and have unpleasant side effects and are difficult to discontinue.
While a medication that has an increased dopamine effect may be just the thing for people whose difficulties stem from dopamine processing, it might not be the best thing for people who've had trouble with anxiety from medications that inhibit norepinephrine reuptake. Just my opinion. . .
The company has a description of Neurovance up, and I wanted to share this piece -
The pharmacology of EB-1020 suggests a profile similar to atomoxetine (the first non-stimulant approved for ADHD), but with an additional effect on DA. This could improve attention and problem solving activity, as well as lead to a faster speed of onset and an improved cognitive profile. In a study conducted at Harvard by Frank Tarazi, Ph.D., EB-1020 showed positive results in an animal model for ADHD. While the DA neurotransmission brings important benefits in ADHD treatment, EB-1020 features moderate DA reuptake resulting in the potential for a lower risk of drug abuse liability than stimulants such as mixed amphetamine salts or methylphenidate used in the treatment of ADHD. Since these stimulants are frequently diverted for non-medicinal purposes, the Federal government exerts strong controls over these addictive medications.
Personally, I'm skeptical of the overuse of/addiction to stimulants idea that propels a lot of this research and gets so much media attention. If you actually have ADHD, you're not all that likely to have a problem with stimulants. OTOH, medications like these work more like antidepressants (and sometimes antipsychotics) and take a while to start working and have unpleasant side effects and are difficult to discontinue.
While a medication that has an increased dopamine effect may be just the thing for people whose difficulties stem from dopamine processing, it might not be the best thing for people who've had trouble with anxiety from medications that inhibit norepinephrine reuptake. Just my opinion. . .