Post by Amtram on Mar 3, 2014 13:07:19 GMT -5
Although research into the genetic basis of ADHD is a slow go, it's not pointless. It's pretty clear that ADHD is a permanent condition for at least half of us (possibly more) which means that our brains are somehow different right from the start. That means. . .genetics. And no, I don't believe it's as simple as dopamine, so I'm going to include a few other things.
Not everything is available as full text, sorry.
Characterizing the ADHD Phenotype for genetic studies goes back to 2005, but has some good background information about the basis for establishing a phenotype, and some of the research that created the standards.
Attention deficit/hyperactivity disorder (ADHD): Complex phenotype, simple genotype? is from 2004, and combines information that justifies the search for a phenotype along with a lot of information about confounding factors in compiling information from different research sources.
Neurobiology of Attention Deficit/Hyperactivity Disorder is newer, but as a meta-analysis, serves to provide more source information than robust data. Lots of links, but most of them will be to abstracts only. I include it mostly to show the wide variety of approaches that are being used that support ADHD as a valid phenotype rather than simply a diagnosis based on symptoms.
The genetics of attention deficit/hyperactivity disorder in adults, a review is from 2011 and looks at several of the different candidate genes for ADHD. Meta-analysis with linky goodness.
NOTE: If there's anything in particular here that catches your eye and you want to discuss further, feel free to start a thread on it. If you have additional links to studies on the phenotype or genetics of ADHD, and just want to share them, post away!
Not everything is available as full text, sorry.
Characterizing the ADHD Phenotype for genetic studies goes back to 2005, but has some good background information about the basis for establishing a phenotype, and some of the research that created the standards.
Attention deficit/hyperactivity disorder (ADHD): Complex phenotype, simple genotype? is from 2004, and combines information that justifies the search for a phenotype along with a lot of information about confounding factors in compiling information from different research sources.
Neurobiology of Attention Deficit/Hyperactivity Disorder is newer, but as a meta-analysis, serves to provide more source information than robust data. Lots of links, but most of them will be to abstracts only. I include it mostly to show the wide variety of approaches that are being used that support ADHD as a valid phenotype rather than simply a diagnosis based on symptoms.
The genetics of attention deficit/hyperactivity disorder in adults, a review is from 2011 and looks at several of the different candidate genes for ADHD. Meta-analysis with linky goodness.
NOTE: If there's anything in particular here that catches your eye and you want to discuss further, feel free to start a thread on it. If you have additional links to studies on the phenotype or genetics of ADHD, and just want to share them, post away!